Endocrine Abstracts

BackgroundPituitary adenomas are general benign tumors. However, gross invasion at time of operation is observed in up to 35% of pituitary adenomas. The new WHO classification describes pituitary tumor subtypes along with histological markers, such as Ki67 > 3%, that may suggest a potential for aggressive clinical behavior. The expression of EGFR in tumor microenvironment of pituitary adenomas ant its correlation with tumor behavior have been poorly ...

IntroductionThe use of antithyroid drugs is associated rarely with severe hepatotoxicity. Recently, due to several cases reported in the literature, acute pancreatitis was added as a severe potential adverse effect induced by methimazole. The physiopathology of methimazole induced pancreatitis is not fully understood (intrinsic toxicity or idiosyncratic drug reaction were proposed as possible mechanisms). If adverse effects occur and no other treatment o...